SH3BGR

SH3BGR
Identifiers
Aliases	SH3BGR, 21-GARP, SH3 domain binding glutamate rich protein
External IDs	OMIM: 602230; HomoloGene: 137201; GeneCards: SH3BGR; OMA:SH3BGR - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	39,515,506 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; skeletal muscle tissue; ; muscle of thigh; ; left ventricle; ; apex of heart; ; right auricle; ; right coronary artery; ; ascending aorta; ; Descending thoracic aorta; ; left coronary artery;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SH3 domain binding;
Cellular component	cytosol;
Biological process	positive regulation of signal transduction; protein-containing complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	6450
	n/a
	ENSG00000185437
	n/a
	P55822
	n/a
	NM_001001713; NM_007341; NM_001317740; NM_001317741; NM_001317742
	n/a
	NP_001001713; NP_001304669; NP_001304670; NP_001304671; NP_031367
	n/a
	Wikidata
View/Edit Human

SH3 domain-binding glutamic acid-rich protein is a protein that in humans is encoded by the SH3BGR gene.^[3]^[4]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185437 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Scartezzini P, Egeo A, Colella S, Fumagalli P, Arrigo P, Nizetic D, Taramelli R, Rasore-Quartino A (Mar 1997). "Cloning a new human gene from chromosome 21q22.3 encoding a glutamic acid-rich protein expressed in heart and skeletal muscle". Hum Genet. 99 (3): 387–92. doi:10.1007/s004390050377. PMID 9050928. S2CID 40468995.
^ "Entrez Gene: SH3BGR SH3 domain binding glutamic acid-rich protein".

Hu YH, Warnatz HJ, Vanhecke D, et al. (2006). "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins". BMC Genomics. 7: 155. doi:10.1186/1471-2164-7-155. PMC 1526728. PMID 16780588.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Sandri C, Di Lisi R, Picard A, et al. (2004). "Heart morphogenesis is not affected by overexpression of the Sh3bgr gene mapping to the Down syndrome heart critical region". Hum. Genet. 114 (5): 517–9. doi:10.1007/s00439-004-1088-8. PMID 14767758. S2CID 9986804.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Jiang LQ, Wen SJ, Wang HY, Chen LY (2003). "Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system". Hypertens. Res. 25 (4): 647–52. doi:10.1291/hypres.25.647. PMID 12358155.
Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. Bibcode:2000Natur.405..311H. doi:10.1038/35012518. PMID 10830953.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

This article on a gene on human chromosome 21 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000185437 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9050928-3] Scartezzini P, Egeo A, Colella S, Fumagalli P, Arrigo P, Nizetic D, Taramelli R, Rasore-Quartino A (Mar 1997). "Cloning a new human gene from chromosome 21q22.3 encoding a glutamic acid-rich protein expressed in heart and skeletal muscle". Hum Genet. 99 (3): 387–92. doi:10.1007/s004390050377. PMID 9050928. S2CID 40468995.

[entrez-4] "Entrez Gene: SH3BGR SH3 domain binding glutamic acid-rich protein".

[3]

[4]

[1]

[2]

SH3BGR

See also

References

Further reading