This family represents the SL1 RNA. The gene encoding SL1 RNA is commonly, but not always, located in the spacer region between 5S-rRNA genes. The SL1 RNA is involved in trans-splicing, which is a form of RNA processing. The acquisition of a spliced leader from an SL RNA is an inter-molecular reaction that precisely joins exons derived from separately transcribed RNAs. This mechanism of mRNA maturation has been shown to occur in a number of lower eukaryotes and is commonplace in nematodes.[1]
| SL1 RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of SL1 | |
| Identifiers | |
| Symbol | SL1 |
| Rfam | RF00198 |
| Other data | |
| RNA type | Gene |
| Domain(s) | Eukaryota |
| GO | GO:0000365 |
| SO | SO:0000233 |
| PDB structures | PDBe |
References
edit- ^ Dassanayake RS, Chandrasekharan NV, Karunanayake EH (May 2001). "Trans-spliced leader RNA, 5S-rRNA genes and novel variant orphan spliced-leader of the lymphatic filarial nematode Wuchereria bancrofti, and a sensitive polymerase chain reaction based detection assay". Gene. 269 (1–2): 185–193. doi:10.1016/S0378-1119(01)00438-3. PMID 11376950.
External links
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