Solute carrier family 25 member 39 is a protein that in humans is encoded by the SLC25A39 gene.[5][6] The protein has been shown to be necessary for the import of the major antioxidant glutathione into the mitochondria. [7][8]

SLC25A39
Identifiers
AliasesSLC25A39, CGI69, CGI-69, solute carrier family 25 member 39
External IDsOMIM: 610820; MGI: 1196386; HomoloGene: 69200; GeneCards: SLC25A39; OMA:SLC25A39 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001143780
NM_016016
NM_001321240
NM_001321241
NM_001366726

NM_026542

RefSeq (protein)

NP_001137252
NP_001308169
NP_001308170
NP_057100
NP_001353655

NP_080818

Location (UCSC)Chr 17: 44.32 – 44.32 MbChr 11: 102.29 – 102.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000013306Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000018677Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Haitina T, Lindblom J, Renstrom T, Fredriksson R (Nov 2006). "Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system". Genomics. 88 (6): 779–90. doi:10.1016/j.ygeno.2006.06.016. PMID 16949250.
  6. ^ "Entrez Gene: SLC25A39 solute carrier family 25, member 39".
  7. ^ Wang Y, Yen FS, Zhu XG, Timson RC, Weber R, Xing C, Liu Y, Allwein B, Luo H, Yeh H, Heissel S, Unlu G, Gamazon ER, Kharas MG, Hite R, Birsoy K (Nov 2021). "SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells". Nature. 599 (7883): 136–140. Bibcode:2021Natur.599..136W. doi:10.1038/s41586-021-04025-w. PMC 10981497. PMID 34707288. S2CID 240072540.
  8. ^ "Scientists discover how mitochondria import antioxidants". Retrieved January 22, 2022.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.