SPATA2

Spermatogenesis-associated protein 2 is a protein that in humans is encoded by the SPATA2 gene.

SPATA2
Identifiers
Aliases	SPATA2, PD1, PPP1R145, tamo, spermatogenesis associated 2
External IDs	OMIM: 607662; MGI: 2146885; HomoloGene: 4407; GeneCards: SPATA2; OMA:SPATA2 - orthologs
Gene location (Human) Chr. Chromosome 20 (human) Band 20q13.13 Start 49,903,391 bp End 49,915,529 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 H3 Start 167,323,053 bp End 167,334,807 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte middle temporal gyrus endothelial cell Brodmann area 23 primary visual cortex right frontal lobe prefrontal cortex Brodmann area 9 C1 segment caudate nucleus Top expressed in otic vesicle lobe of cerebellum zygote cerebellar vermis dentate gyrus of hippocampal formation granule cell subiculum visual cortex primary motor cortex primary visual cortex hippocampus proper More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding molecular function Cellular component cytoplasm nucleus fibrillar center Biological process multicellular organism development cell differentiation spermatogenesis regulation of tumor necrosis factor-mediated signaling pathway regulation of inflammatory response regulation of necroptotic process protein K63-linked deubiquitination protein linear deubiquitination programmed cell death Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9825 263876 Ensembl ENSG00000158480 ENSMUSG00000047030 UniProt Q9UM82 Q8K004 RefSeq (mRNA) NM_001135773 NM_006038 NM_170756 NM_001356523 RefSeq (protein) NP_001129245 NP_006029 NP_001343452 NP_739562 Location (UCSC) Chr 20: 49.9 – 49.92 Mb Chr 2: 167.32 – 167.33 Mb PubMed search
Wikidata
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Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
• Graziotto R, Foresta C, Scannapieco P, et al. (1999). "cDNA cloning and characterization of PD1: a novel human testicular protein with different expressions in various testiculopathies". Exp. Cell Res. 248 (2): 620–6. doi:10.1006/excr.1999.4449. PMID 10222154.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Liliana Slongo M, Zotti L, Onisto M (2003). "Cloning and characterization of the promoter region of human spata2 (spermatogenesis-associated protein 2) gene". Biochim. Biophys. Acta. 1625 (2): 192–6. doi:10.1016/s0167-4781(02)00594-8. PMID 12531478.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.