Speedy protein A is a protein that in humans is encoded by the SPDYA gene.[5][6][7][8]

SPDYA
Identifiers
AliasesSPDYA, RINGO3, RINGOA, SPDY1, SPY1, speedy/RINGO cell cycle regulator family member A
External IDsOMIM: 614029; MGI: 1918141; HomoloGene: 16357; GeneCards: SPDYA; OMA:SPDYA - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_182756
NM_001008779
NM_001142634

NM_001142631
NM_029254

RefSeq (protein)

NP_001008779
NP_001136106
NP_877433

NP_001136103
NP_083530

Location (UCSC)Chr 2: 28.78 – 28.85 MbChr 17: 71.86 – 71.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

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SPDYA has been shown to interact with CDKN1B.[9]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163806Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052525Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Porter LA, Dellinger RW, Tynan JA, Barnes EA, Kong M, Lenormand JL, Donoghue DJ (Apr 2002). "Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2". The Journal of Cell Biology. 157 (3): 357–66. doi:10.1083/jcb.200109045. PMC 2173287. PMID 11980914.
  6. ^ Barnes EA, Porter LA, Lenormand JL, Dellinger RW, Donoghue DJ (Jul 2003). "Human Spy1 promotes survival of mammalian cells following DNA damage". Cancer Research. 63 (13): 3701–7. PMID 12839962.
  7. ^ Cheng A, Xiong W, Ferrell JE, Solomon MJ (Jan 2005). "Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins". Cell Cycle. 4 (1): 155–65. doi:10.4161/cc.4.1.1347. PMID 15611625.
  8. ^ "Entrez Gene: SPDYA speedy homolog A (Drosophila)".
  9. ^ Porter LA, Kong-Beltran M, Donoghue DJ (Sep 2003). "Spy1 interacts with p27Kip1 to allow G1/S progression". Molecular Biology of the Cell. 14 (9): 3664–74. doi:10.1091/mbc.E02-12-0820. PMC 196558. PMID 12972555.

Further reading

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