STRO-1 (Stro-1 in mouse, rat, etc.) is a gene for a protein marker of mesenchymal stem cells (MSC). Molecular mass of Stro-1 is 75kD. The name STRO-1 is firstly proposed in the 1990s' as the name of an anti-CD34+-mesenchymal-stem-cell monoclonal antibody. The name "STRO-1" consists of STRO, which means mesenchyme, and "1", which means it's the first isolated monoclonal antibody to identify mesenchymal stem cells. The term "STRO-1" then was applied to the antigen for this antibody. In human body, STRO-1 exists in many organs, like lung and liver.[1][2][3]
See also
edit- Mesenchymal stem cells (MSC)
References
edit- ^ Lin, Guiting; Liu, Gang; Banie, Lia; Wang, Guifang; Ning, Hongxiu; Lue, Tom F.; Lin, Ching-Shwun (October 2011). "Tissue Distribution of Mesenchymal Stem Cell Marker Stro-1". Stem Cells and Development. 20 (10): 1747–1752. doi:10.1089/scd.2010.0564. PMC 3182037. PMID 21208041.
- ^ Ning, H; Lin, G; Lue, TF; Lin, CS (23 September 2011). "Mesenchymal stem cell marker Stro-1 is a 75 kd endothelial antigen". Biochemical and Biophysical Research Communications. 413 (2): 353–7. doi:10.1016/j.bbrc.2011.08.104. PMC 3183308. PMID 21903091.
- ^ "Anti-STRO1 antibody [STRO-1]". Abcam. Retrieved 2018-02-13.
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