Sulfotransferase 1C4 is an enzyme that in humans is encoded by the SULT1C4 gene .[ 3] [ 4] [ 5]
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters , drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities.
The gene structure (number and length of exons ) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds.[ 5]
^ a b c GRCh38: Ensembl release 89: ENSG00000198075 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Freimuth RR, Raftogianis RB, Wood TC, Moon E, Kim UJ, Xu J, Siciliano MJ, Weinshilboum RM (Jul 2000). "Human sulfotransferases SULT1C1 and SULT1C2: cDNA characterization, gene cloning, and chromosomal localization". Genomics . 65 (2): 157–65. doi :10.1006/geno.2000.6150 . PMID 10783263 . ^ Sakakibara Y, Yanagisawa K, Katafuchi J, Ringer DP, Takami Y, Nakayama T, Suiko M, Liu MC (Jan 1999). "Molecular cloning, expression, and characterization of novel human SULT1C sulfotransferases that catalyze the sulfonation of N-hydroxy-2-acetylaminofluorene" . J Biol Chem . 273 (51): 33929–35. doi :10.1074/jbc.273.51.33929 PMID 9852044 . ^ a b "Entrez Gene: SULT1C2 sulfotransferase family, cytosolic, 1C, member 2" .
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