SYT-510 is an endocannabinoid reuptake inhibitor, or "selective endocannabinoid reuptake inhibitor" ("SERI"), which is under development for the treatment of anxiety disorders, mood disorders, and traumatic stress disorders.[2][1][3][4] It is said to mildly and selectively increase levels of endocannabinoids like anandamide via inhibition of a newly identified biological target.[4][2] As of January 2024, the drug is in the preclinical stage of development or is entering phase 1 clinical trials for the preceding indications.[2][1][4][3] It is under development by a pharmaceutical company called Synendos Therapeutics.[2][1][3]
| Clinical data | |
|---|---|
| Other names | SYT510 |
| Routes of administration | Oral[1] |
| Drug class | Endocannabinoid reuptake inhibitor[2] |
References
edit- ^ a b c d "Delving into the Latest Updates on SYT-510 with Synapse". Synapse. 4 August 2024. Retrieved 15 August 2024.
- ^ a b c d e "SYT 510". AdisInsight. 22 January 2024. Retrieved 15 August 2024.
- ^ a b c Gertsch J, Chicca A (July 2024). "CNS Drug Discovery in Academia: Where Basic Research Meets Innovation". ChemBioChem: e202400397. doi:10.1002/cbic.202400397. PMID 38958639.
Five years after incorporation, Synendos Therapeutics has completed non-clinical development of the [selective endocannabinoid reuptake inhibitor (SERI)] drug candidate SYT-510 and has initiated Phase 1 clinical development in healthy volunteers, marking the significant transition into a clinical stage biotech company. The mission of Synendos is to develop breakthrough safe and effective therapies for neurological and neuropsychiatric disorders through modulation of the [endocannabinoid system (ECS)] with SERIs to enable restoration of the natural functioning of the brain.
- ^ a b c Therapeutics, Synendos (18 January 2024). "Synendos Therapeutics AG Granted EMA Clinical Trial Authorisation for first-in-class Endocannabinoid System modulator, SYT-510". PR Newswire. Retrieved 15 August 2024.
External links
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