Saint Zoe may refer to:
- Zoe of Rome (d. ca. 286), noblewoman, wife of Nicostratus, a high Roman court official. Later saint
- Zoe (died 127 AD), wife of Exuperius, 2nd century Christian martyr alongside Exuperius (see Exuperius and Zoe)
This disambiguation page lists articles associated with the title Saint Zoe.
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