Sainte-Sabine is a commune in the Côte-d'Or department in eastern France.
Sainte-Sabine (French for Saint Sabina) may also refer to:
- Sainte-Sabine, Chaudière-Appalaches, Quebec, Canada, a municipality
- Sainte-Sabine, Montérégie, Quebec, Canada, a municipality
- Sainte-Sabine-Born, a commune in the Dordogne department, southwestern France
- Sainte-Sabine-sur-Longève, a commune in the Sarthe department, Pays-de-la-Loire, north-western France