Salicylate decarboxylase

Salicylate decarboxylase (EC 4.1.1.91, salicylic acid decarboxylase, Scd) is an enzyme with systematic name salicylate carboxy-lyase.[1] This enzyme catalyses the following chemical reaction

Salicylate decarboxylase
Identifiers
EC no.4.1.1.91
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
salicylate phenol + CO2

In the reverse direction the enzyme catalyses the regioselective carboxylation of phenol into salicylate.

References

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  1. ^ Kirimura K, Gunji H, Wakayama R, Hattori T, Ishii Y (April 2010). "Enzymatic Kolbe-Schmitt reaction to form salicylic acid from phenol: enzymatic characterization and gene identification of a novel enzyme, Trichosporon moniliiforme salicylic acid decarboxylase". Biochemical and Biophysical Research Communications. 394 (2): 279–84. doi:10.1016/j.bbrc.2010.02.154. PMID 20188702.
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