Sam Boyd (1910–1993) was an American entrepreneur, casino manager and developer.
Sam or Samuel Boyd is also the name of:
- Sam Boyd (American football) (1914–2001), head football coach at Baylor University
- Samuel Boyd (Florida politician) (1847–1942), Florida state legislator
- Samuel Becket Boyd II (1865–1929), Chief of the Knoxville, Tennessee, fire department
- Samuel Boyd (Northern Ireland politician) (1886/87–?), member of the Senate of Northern Ireland
- Samuel Leonard Boyd, Australian multiple murderer