Samalizumab is a humanized monoclonal antibody designed for oncology indications.[1] Samalizumab is a recombinant humanized monoclonal antibody that targets the immunoregulatory protein CD200. Results from a Phase I study indicated the drug has potential for use in treating cancers including chronic lymphocytic leukemia. [2]
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Humanized (from mouse) |
| Target | CD200 |
| Clinical data | |
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| Identifiers | |
| CAS Number | |
| ChemSpider |
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| UNII | |
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| Chemical and physical data | |
| Formula | C6542H10086N1702O2102S46 |
| Molar mass | 147687.22 g·mol−1 |
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Samalizumab was developed by Alexion Pharmaceuticals.
References
edit- ^ "Statement On A Nonproprietary Name Adopted By The USAN Council: Samalizumab" (PDF). American Medical Association.
- ^ "Phase I study of samalizumab in chronic lymphocytic leukemia and multiple myeloma: blockade of the immune checkpoint CD200". J Immunother Cancer 2019 Aug 23;7(1):227. doi: 10.1186/s40425-019-0710-.
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