Santa Ana winds are strong seasonal winds in Southern California, United States, and northern Baja California, Mexico.
Santa Ana winds may also refer to:
- Santa Ana Wind (song), 2012 song by Everclear
- Santa Ana Winds (song), 1980 song by The Beach Boys
- Santa Ana Winds (album), 1984 album by Steve Goodman
- Santa Ana Winds FC, a soccer team in the United Premier Soccer League
- Santa Ana Winds Youth Band, a marching band based in Orange County, California