Santana do Manhuaçu is a Brazilian municipality located in the state of Minas Gerais. The city belongs to the mesoregion of Zona da Mata and to the microregion of Manhuaçu. As of 2020, the estimated population was 8,667.[1]

Location of Santana do Manhuaçu within Minas Gerais

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20°06′28″S 41°55′30″W / 20.10778°S 41.92500°W / -20.10778; -41.92500