Sarah Hughes (born 1985) is an American figure skater.
Sarah Hughes or Sara Hughes may also refer to:
- Sara Hughes (born 1995), American beach volleyball player
- Sara Hughes (artist) (born 1971), Canadian-born New Zealand artist
- Sarah Hughes (journalist) (1972–2021), British journalist
- Sarah A. Hughes (1847-1816), African Methodist Episcopal preacher
- Sarah T. Hughes (1896–1985), US District Court judge
- Sarah Hughes, (?–1574), Fictional character in the Hellboy franchise, being Hellboy's biological mother.
- Sarah Hewson (née Hughes), British news reporter