School of Engineering and Applied Science is the name of several engineering schools at universities in the United States:
- Fu Foundation School of Engineering and Applied Science at Columbia University, founded in 1896
- Fred DeMatteis School of Engineering and Applied Science at Hofstra University in New York
- George Washington University School of Engineering and Applied Science at George Washington University
- Harvard School of Engineering and Applied Sciences at Harvard University
- Henry Samueli School of Engineering and Applied Science at the University of California, Los Angeles
- Robert R. McCormick School of Engineering and Applied Science at Northwestern University
- University of Michigan School for Environment and Sustainability at the University of Michigan, founded in 1927
- University of Pennsylvania School of Engineering and Applied Science at the University of Pennsylvania, founded in 1852
- University of Virginia School of Engineering and Applied Science at the University of Virginia, founded in 1836
- Princeton University School of Engineering and Applied Science
- University at Buffalo School of Engineering and Applied Sciences
- Washington University School of Engineering and Applied Science at Washington University in St. Louis, founded in 1854