Senator Barker may refer to:
- George Barker (Virginia politician) (born 1951), Virginia State Senate
- H. W. Barker (1860–1950), Wisconsin State Senate
- Jacob Barker (1779–1871), New York State Senate
- James A. Barker (1858–1943), Wisconsin State Senate
- Lewis Barker (politician) (1818–1890), Maine State Senate
- Robert L. Barker (died 2010), North Carolina State Senate