Senator Lopez or López may refer to:
- Carlos Dávila López (fl. 1990s–2000s), Senate of Puerto Rico
- Ernesto Lopez (fl. 2000s–2010s), Delaware State Senate
- Fernando Lopez (1904–1993), Senate of the Philippines
- Joe Eddie Lopez (born 1939), Arizona State Senate
- Juan Hernández López (1859–1944), Senate of Puerto Rico
- Linda J. Lopez (born 1948), Arizona State Senate
- Linda M. Lopez (born 1964), New Mexico State Senate
- Luis Negrón López (1909–1991), Senate of Puerto Rico