Senator Mack may refer to:
- Andrew Mack (1780–1854), Michigan State Senate
- Connie Mack III (born 1940), U.S. Senator from Florida
- Ebenezer Mack (1791–1849), New York State Senate
- Joseph Mack (politician) (1919–2005), Michigan State Senate
- Mike Mack (1873–1949), Wisconsin State Senate