Senator Otis may refer to:
- George L. Otis (1829–1882), Minnesota State Senate
- Harrison Gray Otis (politician) (1765–1848), U.S. Senator from Massachusetts
- James Otis (New York politician) (1836–1898), New York State Senate
- John Otis (Maine politician) (1801–1856), Maine State Senate
This disambiguation page lists articles associated with the title Senator Otis.
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