Senator Payne may refer to:
Members of the United States Senate
edit- Frederick G. Payne (1904–1978), U.S. Senator from Maine from 1953 to 1959
- Henry B. Payne (1810–1896), U.S. Senator from Ohio from 1885 to 1891
United States state senate members
edit- Chuck Payne (born 1964), Georgia State Senate
- Elisha Payne (1731–1807), New Hampshire State Senate
- Franklin Payne (died 1994), Missouri State Senate
- Harry Vearle Payne (1908–1984), New Mexico State Senate
- Lewis S. Payne (1819–1898), New York State Senate
- William Payne (New Mexico politician) (born 1951), New Mexico State Senate