Seppelt is a German surname. Notable people with the surname include:

  • Benno Seppelt (1846–1931), South Australian winemaker, son of Joseph
  • Hajo Seppelt (born 1963), German journalist
  • Joseph Ernst Seppelt (1813–1868), founder of Seppeltsfield and the Seppelt winery in South Australia
  • Konrad Seppelt, (born 1944) German chemist, Vice President of the Free University of Berlin

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