Seshan is a surname. Notable people with the surname include:
- Srinivasan Seshan, American computer scientist and professor
- N. K. Seshan (1927–1986), Indian politician
- T. N. Seshan (1932–2019), Former Chief Election Commissioner of India
See also
edit- Seshan, Russia, an abandoned village in Chukotsky District, Chukotka Autonomous Okrug