Sewallis Shirley may refer to:
- Sewallis Edward Shirley, 10th Earl Ferrers (1847–1912), British peer
- Sewallis Shirley (MP) (1844–1904), British politician
- Sewallis Shirley (1709–1765), British MP for Brackley and Callington
This disambiguation page lists articles about people with the same name.
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