Wikipedia

Shalini Prasad

Dr. Shalini Prasad is a biological engineer, Cecil H. and Ida Green Professor of Systems Biology Science, and head of the Bioengineering Department at The University of Texas at Dallas. She was elected to the American Institute for Medical and Biological Engineering College of Fellows in February 2022 "for pioneering contributions in engineering sweat wearables for disease tracking and management for chronic diseases and prognostic monitoring in pandemics."[1] Dr. Shalini Prasad has had a number of faculty positions at many universities. She is the co-founder of a small technology company called EnLiSense LLC. And her research consists of developing technology to monitor individuals to benefit the health industry.

Education

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At the University of Madras located in India, Dr. Shalini Prasad obtained her bachelor's degree of Electronics and Communications Engineering. She then obtained her Ph.D. of Electrical Engineering at the University of California, Riverside.[2]

Career

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According to Dr. Shalini Prasad's LinkedIn, she has held an array of faculty positions at a range of different colleges. She was an Assistant Professor at Portland State University from January 2005 to August 2008 and at Arizona State University from August 2008 to August 2010. She was an Associate Professor at Wichita State University from August 2010 to August 2011. She currently works at the University of Texas, Dallas as a Professor and has worked there since August 2011.[3]

Apart from achieving numerous faculty positions throughout her career, Shalini prasad has also been one of the authors of numerous articles about her research. These articles are published by the National Library of Medicine, and they cover lots of her research. Some of these articles include detecting THC from saliva, being able to monitor patients with brain injuries, and being able to determine blood alcohol levels through sweat. Some of her more recent articles from 2023 consist of the development of a wearable device to monitor chronic diseases,[4] as well as being able to detect electrochemical biomolecules through Transition Metal Dichalcogenides.[5]

Research

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In 2017, Prasad led a team of bioengineers to create a device that could detect elevated blood-sugar from sweat.[6][7] In 2020, she led a study to develop an assay that could be used to detect and measure the concentration of THC from cannabis in saliva.[8] In 2021, Prasad developed a biosensor, which uses the same technology as the sweat analysis device from 2017, with the addition that the device can now detect cortisol.[9]

Another part of Dr. Shalini Prasad's research includes developing a sensor that monitor's patients after suffering a Traumatic Brain Injury by monitoring their sweat to help find ways to treat the patient. This sensor works by monitoring two specific proteins called GFAP and IL-6 in sweat.[10] In addition, Dr. Shalini Prasad's research includes monitoring the neurotransmitter called acetylcholine in the nervous system, which helps monitor many types of brain diseases that could be affecting different individuals.[11]

Entrepreneurship

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In 2014, Shalini Prasad and Sriram Muthukumar cofounded the company EnLiSense LLC, which develops biosensors such as their EnLiSense sensor technology.[12][13] EnLiSense LLC has developed a wearable bracelet-like device that monitors an individual’s alcohol consumption by monitoring their sweat.[14] Ethyl Glucuronide, as well as Ethanol, are substances found in alcohol and are what is being tracked by this device. The wearable device makes direct contact with the skin, and when the user sweats, the device analyses how much alcohol the user has consumed and will send the user results to their smartphone. This information gathered from the user’s sweat measures their blood alcohol levels, and is therefore able to monitor alcohol consumption, even if the alcohol consumption is a small amount.[15]

References

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  1. ^ "Shalini Prasad, Ph.D." American Institute for Medical and Biological Engineering. Retrieved April 25, 2022.
  2. ^ "Shalini Prasad - Bioengineering | The University of Texas at Dallas". be.utdallas.edu. Retrieved 2024-03-20.
  3. ^ Prasad, Shalini. "LinkedIn". LinkedIn. Retrieved 2024-03-20.
  4. ^ Upasham, Sayali; Pali, Madhavi; Jagannath, Badrinath; Lin, Kai-Chun; Prasad, Shalini (2023). "Electrochemical Aptasensing for Lifestyle and Chronic Disease Management". Current Medicinal Chemistry. 30 (8): 895–909. doi:10.2174/0929867329666220520111715. ISSN 1875-533X. PMID 35619314.
  5. ^ Madhurantakam, Sasya; Mathew, Georgeena; David, Bianca Elizabeth; Naqvi, Aliya; Prasad, Shalini (2023-11-22). "Recent Progress in Transition Metal Dichalcogenides for Electrochemical Biomolecular Detection". Micromachines. 14 (12): 2139. doi:10.3390/mi14122139. ISSN 2072-666X. PMC 10745343. PMID 38138308.
  6. ^ "CBS News - Researcher: New Wearable Sweat-Sensing Device Measures Blood Sugar". CBS News.
  7. ^ "KERA News - This Coin-Sized Sensor Could Help Detect Risk For Type 2 Diabetes Without Finger Pricking". 12 July 2017.
  8. ^ "Forbes - This Cannabis Saliva Test Could One Day Be Used To Detect Impaired Driving". Forbes.
  9. ^ "IEEE Spectrum - Stress Levels Revealed in Micro-Beads of Sweat".
  10. ^ Shahub, Sarah; Lin, Kai-Chun; Muthukumar, Sriram; Prasad, Shalini (2022-11-30). "A Proof-of-Concept Electrochemical Skin Sensor for Simultaneous Measurement of Glial Fibrillary Acidic Protein (GFAP) and Interleukin-6 (IL-6) for Management of Traumatic Brain Injuries". Biosensors. 12 (12): 1095. doi:10.3390/bios12121095. ISSN 2079-6374. PMC 9775589. PMID 36551062.
  11. ^ Chen, Jie; Lin, Kai-Chun; Prasad, Shalini; Schmidtke, David W. (2023-09-01). "Label free impedance based acetylcholinesterase enzymatic biosensors for the detection of acetylcholine". Biosensors & Bioelectronics. 235: 115340. doi:10.1016/j.bios.2023.115340. ISSN 1873-4235. PMID 37216844.
  12. ^ "Tracxn - EnLiSense".
  13. ^ "Texas Monthly - Sepsis Kills Millions Each Year. This UT-Dallas Device Aims to Stop That". 10 February 2021.
  14. ^ "AWARE A Wearable Awareness with Real time Exposure Rapid Wearable Alcohol Diagnostics | SBIR.gov". www.sbir.gov. Retrieved 2024-03-19.
  15. ^ "AWARE A Wearable Awareness with Real time Exposure Rapid Wearable Alcohol Diagnostics | SBIR.gov". www.sbir.gov. Retrieved 2024-03-19.
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