Shiono (written: 塩野 lit. "salt field") is a Japanese surname. Notable people with the surname include:
- Akihisa Shiono (塩野 瑛久, born 1995), Japanese actor and model
- Anri Shiono (塩野 アンリ), Japanese voice actress
- Etorouji Shiono (塩野干支郎次, born 1976), Japanese manga artist
- Nanami Shiono (塩野 七生, born 1937), Japanese writer
- Suehiko Shiono (塩野 季彦, 1880–1949), Japanese lawyer and politician