Shuster (originally a spelling variant of Schuster) is the surname of several people:
- Bill Shuster (born 1961), American politician from Pennsylvania
- Bud Shuster (1932–2023), American politician, father of Bill
- David Shuster (born 1967), American reporter
- Frank Shuster (1916–2002), Canadian comedian
- George Nauman Shuster (1894-1977), American academic
- Jared Shuster (born 1998), American baseball player
- Joe Shuster (1914–1992), Canadian comic book artist
- John Shuster (born 1982), American curler
- Mike Shuster (1947–2023), American journalist
- Noam Shuster-Eliassi (born 1986/87), Israeli comedian and activist
- Rosie Shuster (born 1950), Canadian comedy writer
- Savik Shuster (born 1952), Ukrainian journalist
- Suzy Shuster (born 1971/72), reporter
- Will Shuster (1893–1969), American artist
- William Morgan Shuster (1877–1960), American diplomat