Siege of Edessa may refer to:
- Siege of Edessa (163), Roman–Parthian Wars
- Siege of Edessa (165), Roman–Parthian Wars
- Siege of Edessa (503), Roman–Persian Wars
- Siege of Edessa (544), Roman–Persian Wars
- Siege Of Edessa (606), Roman_Persian Wars
- Siege of Edessa (1144), Crusades
- Siege of Edessa (1146), Crusades
See also
edit- Battle of Edessa, between the Roman and Sassanid Empires, 260