Silafluofen

Silafluofen
Names
	Preferred IUPAC name (4-Ethoxyphenyl)[3-(4-fluoro-3-phenoxyphenyl)propyl]di(methyl)silane
	Other names Eflusilanat; Silonen
Identifiers
CAS Number	105024-66-6 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:39393 ;
ChEMBL	ChEMBL493481 ;
ChemSpider	83448 ;
ECHA InfoCard	100.100.662
PubChem CID	92430;
UNII	F4SX221ILG ;
CompTox Dashboard (EPA)	DTXSID4057924 ;
	InChI InChI=1S/C25H29FO2Si/c1-4-27-21-13-15-23(16-14-21)29(2,3)18-8-9-20-12-17-24(26)25(19-20)28-22-10-6-5-7-11-22/h5-7,10-17,19H,4,8-9,18H2,1-3H3 Key: HPYNBECUCCGGPA-UHFFFAOYSA-N ; InChI=1/C25H29FO2Si/c1-4-27-21-13-15-23(16-14-21)29(2,3)18-8-9-20-12-17-24(26)25(19-20)28-22-10-6-5-7-11-22/h5-7,10-17,19H,4,8-9,18H2,1-3H3 Key: HPYNBECUCCGGPA-UHFFFAOYAS;
	SMILES Fc2ccc(cc2Oc1ccccc1)CCC[Si](c3ccc(OCC)cc3)(C)C;
Properties
Chemical formula	C25H29FO2Si
Molar mass	408.588 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Silafluofen is a fluorinated organosilicon pyrethroid insecticide.^[1]^[2]

Silafluofen is used agriculturally against soil-borne insects such as termites, and as a wood preservative. It is registered in Asia (India, Japan, Taiwan, Vietnam) since at least 1995 for crops such as drupes, tea and rice, but has not been notified or authorised in the European Union for example.^[3]^[4]

References

^ Sieburth, Scott McNeill; Manly, Charles J.; Gammon, Derek W. (1990). "Organosilane insecticides. Part I: biological and physical effects of isosteric replacement of silicon for carbon in etofenprox and MTI 800". Pesticide Science. 28 (3): 289–307. doi:10.1002/ps.2780280308.
^ Showell, G. A.; Mills, J. S. (2003). "Chemistry Challenges in Lead Optimization: Silicon Isosteres in Drug Discovery". Drug Discovery Today. 8 (12): 551–556. doi:10.1016/S1359-6446(03)02726-0. PMID 12821303.
^ "Silafluofen". EU Pesticides database. European Commission. Retrieved 26 January 2022.
^ Katsuda, Yoshio; Minamite, Yoshihiro; Vongkaluang, Charunee (December 2011). "Development of Silafluofen-Based Termiticides in Japan and Thailand". Insects. 2 (4): 532–539. doi:10.3390/insects2040532. PMC 4553446. PMID 26467832.

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[1] Sieburth, Scott McNeill; Manly, Charles J.; Gammon, Derek W. (1990). "Organosilane insecticides. Part I: biological and physical effects of isosteric replacement of silicon for carbon in etofenprox and MTI 800". Pesticide Science. 28 (3): 289–307. doi:10.1002/ps.2780280308.

[2] Showell, G. A.; Mills, J. S. (2003). "Chemistry Challenges in Lead Optimization: Silicon Isosteres in Drug Discovery". Drug Discovery Today. 8 (12): 551–556. doi:10.1016/S1359-6446(03)02726-0. PMID 12821303.

[3] "Silafluofen". EU Pesticides database. European Commission. Retrieved 26 January 2022.

[4] Katsuda, Yoshio; Minamite, Yoshihiro; Vongkaluang, Charunee (December 2011). "Development of Silafluofen-Based Termiticides in Japan and Thailand". Insects. 2 (4): 532–539. doi:10.3390/insects2040532. PMC 4553446. PMID 26467832.

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