In molecular biology, SNORA17 (also known as ACA17) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.[1] Specifically, it is predicted to guide pseudouridylation of the 28S rRNA at positions U4659 and U4598. It shares the same host gene together with ACA43.
| Small nucleolar RNA SNORA17 | |
|---|---|
 Predicted secondary structure and sequence conservation of SNORA17 | |
| Identifiers | |
| Symbol | SNORA17 |
| Alt. Symbols | snoACA17 |
| Rfam | RF00560 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; HACA-box |
| Domain(s) | Eukaryota |
| GO | GO:0006396 GO:0005730 |
| SO | SO:0000594 |
| PDB structures | PDBe |
There are many closely related sequences that do not appear to have conserved H and ACA boxes, and may be pseudogenes.
References
edit- ^ Kiss AM, Jády BE, Bertrand E, Kiss T (July 2004). "Human box H/ACA pseudouridylation guide RNA machinery". Molecular and Cellular Biology. 24 (13): 5797–807. doi:10.1128/MCB.24.13.5797-5807.2004. PMC 480876. PMID 15199136.
Further reading
edit- Ofengand J, Bakin A (February 1997). "Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts". Journal of Molecular Biology. 266 (2): 246–68. doi:10.1006/jmbi.1996.0737. PMID 9047361.
External links
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