In molecular biology, snoRNA SNORD70 (HBII-234) is a non-coding RNA that belongs to the C/D family of snoRNAs.[1] It is the human orthologue of the mouse MBII-234 and is predicted to guide 2'O-ribose methylation of the small 18S rRNA on position A512.[2] It is hosted, together with HBII-95, by the core C/D box snoRNA protein encoding gene NOP5/NOP58.
| Small nucleolar RNA SNORD70 | |
|---|---|
 Predicted secondary structure and sequence conservation of SNORD70 | |
| Identifiers | |
| Symbol | SNORD70 |
| Alt. Symbols | snoHBII-234 |
| Rfam | RF00575 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; C/D-box |
| Domain(s) | Eukaryota |
| GO | GO:0006396 GO:0005730 |
| SO | SO:0000593 |
| PDB structures | PDBe |
References
edit- ^ Lestrade L, Weber MJ (January 2006). "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Research. 34 (Database issue): D158-62. CiteSeerX 10.1.1.105.7552. doi:10.1093/nar/gkj002. PMC 1347365. PMID 16381836.
- ^ Hüttenhofer A, Kiefmann M, Meier-Ewert S, O'Brien J, Lehrach H, Bachellerie JP, Brosius J (June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal. 20 (11): 2943–53. doi:10.1093/emboj/20.11.2943. PMC 125495. PMID 11387227.
External links
edit- Page for Small nucleolar RNA SNORD70 at Rfam
- Entry for HBII-234 at snoRNABase
- Entry in HGNC database[permanent dead link]
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