In molecular biology, SNORD78 (also known as U78) belongs to the C/D family of snoRNAs. It is predicted to guide 2'O-ribose methylation of the large 28S rRNA subunit at position G4593.[1] The snoRNAs U44, U47, U74, U75, U76, U77, U79, U80 and U81, also of the C/D family, share the same host gene with U78 (protein non-coding).[2]
| Small nucleolar RNA SNORD78 | |
|---|---|
 Predicted secondary structure and sequence conservation of SNORD78 | |
| Identifiers | |
| Symbol | SNORD78 |
| Alt. Symbols | snoU78 |
| Rfam | RF00592 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; C/D-box |
| Domain(s) | Eukaryota |
| GO | GO:0006396 GO:0005730 |
| SO | SO:0000593 |
| PDB structures | PDBe |
References
edit- ^ Tycowski KT, Aab A, Steitz JA (November 2004). "Guide RNAs with 5' caps and novel box C/D snoRNA-like domains for modification of snRNAs in metazoa". Current Biology. 14 (22): 1985–95. doi:10.1016/j.cub.2004.11.003. PMID 15556860.
- ^ Lestrade L, Weber MJ (January 2006). "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Research. 34 (Database issue): D158-62. CiteSeerX 10.1.1.105.7552. doi:10.1093/nar/gkj002. PMC 1347365. PMID 16381836.
External links
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