Sodium sulfate symporters are integral membrane proteins that mediate the intake of a wide variety of molecules with the concomitant uptake of sodium ions. These sodium symporters can be grouped, on the basis of sequence and functional similarities into a number of distinct families. One of these families, also known as SLC13 transporters, consists of the following proteins:
- Mammalian sodium/sulphate cotransporter.[1]
- Mammalian renal sodium/dicarboxylate cotransporter,[2] which transports succinate and citrate.
- Mammalian intestinal sodium/dicarboxylate cotransporter.
- Chlamydomonas reinhardtii putative sulphur deprivation response regulator SAC1.[3]
| Na_sulph_symp | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Na_sulph_symp | ||||||||
| Pfam | PF00939 | ||||||||
| Pfam clan | CL0182 | ||||||||
| InterPro | IPR001898 | ||||||||
| PROSITE | PDOC00978 | ||||||||
| TCDB | 2.A.47 | ||||||||
| OPM superfamily | 272 | ||||||||
| OPM protein | 4f35 | ||||||||
| |||||||||
This family also includes a number of bacterial symporters.
References
edit- ^ Markovich D, Forgo J, Stange G, Biber J, Murer H (September 1993). "Expression cloning of rat renal Na+/SO4(2-) cotransport". Proc. Natl. Acad. Sci. U.S.A. 90 (17): 8073–7. doi:10.1073/pnas.90.17.8073. PMC 47290. PMID 7690140.
- ^ Pajor AM (April 1996). "Molecular cloning and functional expression of a sodium-dicarboxylate cotransporter from human kidney". Am. J. Physiol. 270 (4 Pt 2): F642-8. doi:10.1152/ajprenal.1996.270.4.F642. PMID 8967342.
- ^ Davies JP, Yildiz FH, Grossman A (May 1996). "Sac1, a putative regulator that is critical for survival of Chlamydomonas reinhardtii during sulfur deprivation". EMBO J. 15 (9): 2150–9. doi:10.1002/j.1460-2075.1996.tb00568.x. PMC 450137. PMID 8641280.