Somatostatin receptor 3

Shekel Somatostatin receptor type 3 is a protein that in humans is encoded by the SSTR3 gene.[5][6]

SSTR3
Identifiers
AliasesSSTR3, SS-3-R, SS3-R, SS3R, SSR-28, Somatostatin receptor 3
External IDsOMIM: 182453; MGI: 98329; HomoloGene: 20285; GeneCards: SSTR3; OMA:SSTR3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001051
NM_001278687

NM_009218
NM_001356961

RefSeq (protein)

NP_001042
NP_001265616

NP_033244
NP_001343890

Location (UCSC)Chr 22: 37.2 – 37.21 MbChr 15: 78.42 – 78.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.[6]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000278195Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044933Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (February 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics. 15 (2): 449–52. doi:10.1006/geno.1993.1088. PMID 8449518.
  6. ^ a b "Entrez Gene: SSTR3 somatostatin receptor 3".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.