Spyros Spyrou may refer to:
- Spyros Spyrou (politician) (b. 1945), Greek MP and regional governor
- Spyros Spyrou (judoka) (b. 1956), Cypriot judoka
- Spyros Spyrou (runner) (b. 1958), Cypriot middle-distance runner
This disambiguation page lists articles about people with the same name.
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