The SraB RNA is a small non-coding RNA discovered in E. coli during a large scale experimental screen.[1] The 14 novel RNAs discovered were named 'sra' for small RNA, examples include SraC, SraD and SraG.[1] This ncRNA was found to be expressed only in stationary phase.[1] The exact function of this RNA is unknown but it has been shown to affect survival of Salmonella enterica to antibiotic administration in egg albumin.[2] The authors suggest this may be due to SraB regulating a response to components in albumin.
| SraB RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of SraB | |
| Identifiers | |
| Symbol | SraB |
| Alt. Symbols | sraB |
| Rfam | RF00077 |
| Other data | |
| RNA type | Gene; sRNA |
| Domain(s) | Bacteria |
| SO | SO:0000655 |
| PDB structures | PDBe |
See also
editReferences
edit- ^ a b c Argaman, L; Hershberg R; Vogel J; Bejerano G; Wagner EG; Margalit H; Altuvia S (2001). "Novel small RNA-encoding genes in the intergenic regions of Escherichia coli". Curr Biol. 11 (12): 941–950. doi:10.1016/S0960-9822(01)00270-6. PMID 11448770. S2CID 18532334.
- ^ Jiang H, Cao M, Cao X, Gu H, Zeng K (November 2010). "[sRNA (sraB) regulate the resistant ability of Salmonella enterica serovar enteritidis to egg albumen]". Wei Sheng Wu Xue Bao (in Chinese). 50 (11): 1537–1544. PMID 21268901.
External links
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