St. Louis High School may refer to:
- St. Louis Senior High School (Ghana), Kumasi, Ashanti Region
- St Louis High School, Rathmines, Dublin, Ireland
- St. Louis Catholic High School, Lake Charles, Louisiana, US
- Saint Louis School, Honolulu, Hawaii, US
See also
edit- St. Louis University High School, St. Louis, Missouri, US
- Category:High schools in St. Louis, for other high schools in St. Louis, Missouri, US
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