Stone heart syndrome (also known as ischemic contracture) is a rare and serious condition observed in the heart after periods of warm ischemia. It occurs as a complication of cardiopulmonary bypass, and is resistant to several different treatments and interventions, often resulting in death. [1]

The condition is rare, but the outcome typically fatal.[2][3] It was first described by Denton Cooley (1920–2016) in 1972.[4]

References

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  1. ^ Li, Mei; Qin, Zhi; Steen, Erik; Terry, Ann; Wang, Bowen; Wohlfart, Björn; Steen, Stig; Arner, Anders (2023-02-20). "Development and prevention of ischemic contracture ("stone heart") in the pig heart". Frontiers in Cardiovascular Medicine. 10. doi:10.3389/fcvm.2023.1105257. ISSN 2297-055X. PMC 9986286. PMID 36891241.
  2. ^ Cooley, D. A.; Reul, G. J.; Wukasch, D. C. (1975). "Ischemic myocardial contracture ('stone heart'). A complication of cardiac surgery". Israel Journal of Medical Sciences. 11 (2–3): 203–210. PMID 1112706.
  3. ^ Hald, Mathias; Hønge, Jesper; Dall, Rolf Porskjær; Larsen, Signe Holm (January 2018). "Two cases of 'stone heart' with fatal outcome". Journal of Thoracic Disease. 10 (1): E74–E76. doi:10.21037/jtd.2017.12.09. PMC 5863143. PMID 29600109.
  4. ^ Cooley, Denton A.; Reul, George J.; Wukasch, Don C. (April 1972). "Ischemic contracture of the heart: 'Stone heart'". The American Journal of Cardiology. 29 (4): 575–577. doi:10.1016/0002-9149(72)90454-7. PMID 5016840.

Further reading

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