Streptoduocin

Streptoduocin is an aminoglycoside antibiotic.

Streptoduocin

Combination of
Streptomycin	Aminoglycoside antibiotic
Dihydrostreptomycin	Aminoglycoside antibiotic
Clinical data
ATC code	J01GA02 (WHO)
Identifiers
CAS Number	8017-59-2
PubChem CID	202223
ChemSpider	175124
ChEMBL	ChEMBL3833407
Chemical and physical data
3D model (JSmol)	Interactive image
SMILES C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(CO)O.C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(C=O)O
(verify)

It is a mixture of streptomycin and dihydrostreptomycin.

Further reading

• Curry FJ, Schless JM, Storey PB, Wier JA (December 1956). "Ototoxicity from intermittent streptoduocin therapy of pulmonary tuberculosis; a study of one hundred five patients treated eight to ten months". Diseases of the Chest. 30 (6): 628–632. doi:10.1378/chest.30.6.628. PMID 13375456.
• Heyworth F, Helm WH (August 1960). "A comparison of the toxic and allergic reactions occurring with streptomycin and streptoduocin in the treatment of pulmonary tuberculosis". Postgraduate Medical Journal. 36 (418): 516–518. doi:10.1136/pgmj.36.418.516. PMC 2481660. PMID 14401661.
• Francis RS, Gupta SK (August 1958). "The use of corticotrophin in rapid desensitization to PAS". Tubercle. 39 (4): 236–239. doi:10.1016/S0041-3879(58)80074-4. PMID 13581197.
• Shubin H (January 1956). "The preference for streptoduocin in the treatment of tuberculosis of the aging". Journal of the American Geriatrics Society. 4 (1): 65–69. doi:10.1111/j.1532-5415.1956.tb01147.x. PMID 13286067. S2CID 20044460.