Streptonigrin

Streptonigrin is an aminoquinone antitumor and antibacterial antibiotic produced by Streptomyces flocculus. Streptonigrin was a successful target of Total synthesis in 2011.

Streptonigrin

Names
Preferred IUPAC name 5-Amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpyridine-2-carboxylic acid
Identifiers
CAS Number	3930-19-6 Y
ECHA InfoCard	100.021.366
PubChem CID	5351165
UNII	261Q3JB310 Y
CompTox Dashboard (EPA)	DTXSID00960034
Properties
Chemical formula	C25H22N4O8
Molar mass	506.46418
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Notes

• Antitumor antibiotic streptonigrin and its derivatives as inhibitors of nitric oxide-dependent activation of soluble guanylyl cyclase