Sulfametrole

Sulfametrole
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	J01EE03 (WHO) (with trimethoprim);
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 4-amino-N-(4-methoxy-1,2,5-thiadiazol-3-yl)benzenesulfonamide;
CAS Number	32909-92-5;
PubChem CID	64939;
ChemSpider	58466;
UNII	F5AK41IPQG;
KEGG	D08541 ;
ChEBI	CHEBI:88258 ;
CompTox Dashboard (EPA)	DTXSID40865655 ;
ECHA InfoCard	100.046.611
Chemical and physical data
Formula	C9H10N4O3S2
Molar mass	286.32 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COc1c(nsn1)NS(=O)(=O)c2ccc(cc2)N;
	InChI InChI=1S/C9H10N4O3S2/c1-16-9-8(11-17-12-9)13-18(14,15)7-4-2-6(10)3-5-7/h2-5H,10H2,1H3,(H,11,13); Key:IZOYMGQQVNAMHS-UHFFFAOYSA-N;
	(verify)

Sulfametrole (INN) is a sulfonamide antibacterial.

It can be given with trimethoprim.^[1]

References

^ Plummer FA, Nsanze H, D'Costa LJ, et al. (July 1983). "Single-dose therapy of chancroid with trimethoprim-sulfametrole". N. Engl. J. Med. 309 (2): 67–71. doi:10.1056/NEJM198307143090202. PMID 6343878.

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Clinical data


AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	J01EE03 (WHO) (with trimethoprim)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 4-amino-N-(4-methoxy-1,2,5-thiadiazol-3-yl)benzenesulfonamide
CAS Number	32909-92-5
PubChem CID	64939
ChemSpider	58466
UNII	F5AK41IPQG
KEGG	D08541^Y
ChEBI	CHEBI:88258^Y
CompTox Dashboard (EPA)	DTXSID40865655
ECHA InfoCard	100.046.611
Chemical and physical data
Formula	C₉H₁₀N₄O₃S₂
Molar mass	286.32 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES COc1c(nsn1)NS(=O)(=O)c2ccc(cc2)N
InChI InChI=1S/C9H10N4O3S2/c1-16-9-8(11-17-12-9)13-18(14,15)7-4-2-6(10)3-5-7/h2-5H,10H2,1H3,(H,11,13) Key:IZOYMGQQVNAMHS-UHFFFAOYSA-N
(verify)