Sulfoacetaldehyde dehydrogenase (EC 1.2.1.73, SafD) is an enzyme with systematic name 2-sulfoacetaldehyde:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction
| Sulfoacetaldehyde dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.2.1.73 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 2-sulfoacetaldehyde + H2O + NAD+ sulfoacetate + NADH + 2 H+
This reaction is part of a bacterial pathway that can make use the amino group of taurine as a sole source of nitrogen for growth.
References
edit- ^ Krejcík Z, Denger K, Weinitschke S, Hollemeyer K, Paces V, Cook AM, Smits TH (August 2008). "Sulfoacetate released during the assimilation of taurine-nitrogen by Neptuniibacter caesariensis: purification of sulfoacetaldehyde dehydrogenase". Archives of Microbiology. 190 (2): 159–68. doi:10.1007/s00203-008-0386-2. PMID 18506422.
External links
edit- Sulfoacetaldehyde+dehydrogenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
