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Synek (Czech pronunciation: [ˈsɪnɛk]) is Czech surname:
- Jana Synková, a Czechoslovak model-actress
- Jiří Synek, a Czech poet, prose writer, essayist
- Liane Synek (1922, Vienna - 1982), Austrian opera singer
- Ondřej Synek (born 1982, Brandýs nad Labem), a Czech rower