Sze can refer to:
- Alfred Sao-ke Sze (1877–1958), Chinese diplomat
- Sarah Sze (born 1969), American artist
- Simon Sze (born 1936), electrical engineer, professor
- Vivienne Sze, American electrical engineer and computer scientist
- Yi-Kwei Sze (1915–1994), Chinese-born American bass-baritone
For the Cantonese surname, see also: