T2D can refer to:
- Type 2 Diabetes
- Technology Transfer Database
- Type-2 Copper-Depleted
- Douglas T2D, an American twin-engined torpedo bomber, 1927–1937
- River Torrens to Darlington (T2D) section of the North–South Motorway, South Australia.
- T2D.com is a healthcare services company serving consumers that are Type 2 Diabetic.
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