TAS2R20

Taste receptor type 2 member 20 is a protein that in humans is encoded by the TAS2R20 gene.

TAS2R20
Identifiers
Aliases	TAS2R20, T2R20, T2R49, T2R56, TAS2R49, taste 2 receptor member 20
External IDs	OMIM: 613962; MGI: 2681304; HomoloGene: 107105; GeneCards: TAS2R20; OMA:TAS2R20 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) Band 12p13.2 Start 10,995,961 bp End 10,998,304 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6 G1|6 64.03 cM Start 132,754,142 bp End 132,755,125 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum Achilles tendon right ovary left ovary tibial nerve skeletal muscle tissue endometrium gastrocnemius muscle body of uterus stromal cell of endometrium n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity bitter taste receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process sensory perception of taste signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of bitter taste G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 259295 353165 Ensembl ENSG00000282612 ENSG00000255837 ENSG00000273092 ENSMUSG00000053217 UniProt P59543 Q7TQA8 RefSeq (mRNA) NM_176889 NM_181276 RefSeq (protein) NP_795370 NP_851793 Location (UCSC) Chr 12: 11 – 11 Mb Chr 6: 132.75 – 132.76 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

See also

• Taste receptor

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
• Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat. Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
• Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
• Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet. Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440. S2CID 1542970.
• Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.