TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming)
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming) (EC 5.3.2.4, TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase, Tyl1a, dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase) is an enzyme with systematic name dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose:dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose isomerase.[1] This enzyme catalyses the following chemical reaction
| TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.3.2.4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose
The enzyme is involved in biosynthesis of D-mycaminose.
References
edit- ^ Melançon CE, Hong L, White JA, Liu YN, Liu HW (January 2007). "Characterization of TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from the D-mycaminose biosynthetic pathway of Streptomyces fradiae: in vitro activity and substrate specificity studies". Biochemistry. 46 (2): 577–90. doi:10.1021/bi061907y. PMC 2515277. PMID 17209568.
External links
edit- TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase+(dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
