TMSB15A

Thymosin beta-15A is a protein that in humans is encoded by the TMSB15A gene.

TMSB15A
Identifiers
Aliases	TMSB15A, TMSB15, TMSB15B, TMSL8, TMSNB, Tb15, TbNB, thymosin beta 15a
External IDs	OMIM: 300939; GeneCards: TMSB15A; OMA:TMSB15A - orthologs
Gene location (Human) Chr. X chromosome (human) Band Xq22.1 Start 102,513,682 bp End 102,516,739 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in embryo ganglionic eminence ventricular zone testicle gonad periodontal fiber right lung sperm hair follicle glomerulus n/a More reference expression data BioGPS n/a
Gene ontology Molecular function actin binding actin monomer binding molecular function DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoskeleton cytoplasm cellular component Biological process actin filament organization regulation of cell migration sequestering of actin monomers positive regulation of cell migration regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11013 n/a Ensembl ENSG00000158164 n/a UniProt P0CG34 P0CG35 n/a RefSeq (mRNA) NM_021992 n/a RefSeq (protein) NP_001337140 NP_001337141 NP_001337142 NP_919305 NP_068832 NP_068832 n/a Location (UCSC) Chr X: 102.51 – 102.52 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

See also

• Thymosins

Further reading

• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Yokoyama M, Nishi Y, Yoshii J, et al. (1996). "Identification and cloning of neuroblastoma-specific and nerve tissue-specific genes through compiled expression profiles". DNA Res. 3 (5): 311–20. doi:10.1093/dnares/3.5.311. PMID 9039501.
• Bertheau P, Turpin E, Rickman DS, et al. (2007). "Exquisite Sensitivity of TP53 Mutant and Basal Breast Cancers to a Dose-Dense Epirubicin−Cyclophosphamide Regimen". PLOS Med. 4 (3): e90. doi:10.1371/journal.pmed.0040090. PMC 1831731. PMID 17388661.
• Bao L, Loda M, Janmey PA, et al. (1996). "Thymosin beta 15: a novel regulator of tumor cell motility upregulated in metastatic prostate cancer". Nat. Med. 2 (12): 1322–8. doi:10.1038/nm1296-1322. PMID 8946830. S2CID 848538.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Dhaese S, Jonckheere V, Goethals M, et al. (2007). "Functional and profiling studies prove that prostate cancer upregulated neuroblastoma thymosin beta is the true human homologue of rat thymosin beta15". FEBS Lett. 581 (25): 4809–15. doi:10.1016/j.febslet.2007.09.003. PMID 17888914.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gevaert K, Goethals M, Martens L, et al. (2003). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
• Banyard J, Barrows C, Zetter BR (2009). "Differential Regulation of Human Thymosin Beta 15 Isoforms by Transforming Growth Factor Beta 1". Genes Chromosomes Cancer. 48 (6): 502–9. doi:10.1002/gcc.20659. PMC 2756613. PMID 19296525.
• Gu YM, Li SY, Qiu XS, Wang EH (2008). "Elevated thymosin beta15 expression is associated with progression and metastasis of non-small cell lung cancer". APMIS. 116 (6): 484–90. doi:10.1111/j.1600-0463.2008.00918.x. PMID 18754322. S2CID 85038190.