TMTC2

Transmembrane and TPR repeat-containing protein 2 is a protein that in humans is encoded by the TMTC2 gene.

TMTC2
Identifiers
Aliases	TMTC2, IBDBP1, transmembrane and tetratricopeptide repeat containing 2, transmembrane O-mannosyltransferase targeting cadherins 2
External IDs	OMIM: 615856; MGI: 1914057; HomoloGene: 25521; GeneCards: TMTC2; OMA:TMTC2 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) Band 12q21.31 Start 82,686,880 bp End 83,134,870 bp
Gene location (Mouse) Chr. Chromosome 10 (mouse) Band 10|10 D1 Start 105,023,524 bp End 105,410,312 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone corpus callosum mucosa of paranasal sinus ganglionic eminence caput epididymis C1 segment corpus epididymis right uterine tube inferior ganglion of vagus nerve tail of epididymis Top expressed in hand cumulus cell renal capsule body of femur clavicle vas deferens molar left lung lobe olfactory epithelium membranous bone More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding mannosyltransferase activity dolichyl-phosphate-mannose-protein mannosyltransferase activity transferase activity Cellular component integral component of membrane endoplasmic reticulum membrane endoplasmic reticulum membrane Biological process calcium ion homeostasis protein O-linked mannosylation protein glycosylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 160335 278279 Ensembl ENSG00000179104 ENSMUSG00000036019 UniProt Q8N394 Q56A06 RefSeq (mRNA) NM_152588 NM_001320321 NM_001320322 NM_177368 RefSeq (protein) NP_001307250 NP_001307251 NP_689801 NP_796342 Location (UCSC) Chr 12: 82.69 – 83.13 Mb Chr 10: 105.02 – 105.41 Mb PubMed search
Wikidata
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Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.